Swamp People: Serpent Invasion

The series ran 5 seasons across 52 episodes and has finished, so there is no cliffhanger risk.

The Florida Everglades are under siege. An invasion of Burmese pythons is decimating this natural wonder of the South. Entire species of animals are being wiped out. Aggressive, ravenous and incredibly fast-breeding, these pythons have no natural predator to stop them… except for man.