
Biography
Sirena grew up around the U.S. and abroad her mother, Margaret Irwin-Brandon, is a harpsichordist and conductor of a Baroque Orchestra, and her father, John Irwin, was a physicist (with a significant stint as a dropped out hippie)-landed ultimately at Sanford University. After time spent at Northfield Mt. Hermon boarding school where she fell in love with theater, she attended San Francisco State University and graduated with degrees in Theater and International Relations. After a successful stint in a popular San Francisco sketch comedy group, she landed in Los Angeles where her knack for voices and accents were quickly put to use in the world of animation. This ultimately brought her to her successful career as a voice director in animation (thanks to her mentor Andrea Romano!) garnering her an Emmy nomination in 2021.
Acted in 30
2020s
- 2025
- 2024
- 2022
- 2021
- 2020
2010s
- 2019
SpongeBob’s Big Birthday Blowout
SpongeBob’s Mom / Gawky Female / The Kid / Office Worker
- 2018
- 2017
- 2016
SpongeBob LongPants
Fancy Lady Fish / Kid Fish (voice)
- 2015
- 2014
Planes - Vitaminamulch: Air Spectacular
Additional Voice
- 2013
- 2011
SpongeBob’s Runaway Roadtrip
Margret SquarePants (voice)
2000s
- 2008
Can I Be Your Bratwurst, Please?
Movie
- 2007
Electric Apricot
The Photographer
- 2006
Holly Hobbie and Friends: Christmas Wishes
Mrs. Palmer (voice)
So NoTORIous
Cheryl - Tori's Publicist · 1 episode
- 2004
- 2003
- 2002
The Trip
Beverly
- 2001
The Sky is Falling
Gabby
1990s
- 1999
- 1995
- 1994
Produced 3
2020s
- 2023
- 2022
2010s
- 2018